Sunday, 5 May 2019

Lupus in Australian Indigenous communities will be the focus of a new research project

Dr Fabien Vincent
Sometimes when we're dealing with a condition like lupus, it seems like we're in it on our own, and no-one else is doing anything about it.

Actually, someone is doing something about it.  I keep saying that my heroes wear lab-coats.  These are the people who are quietly working to improve the lives, and even save the lives, of lupies around the world.  (With six million of us world-wide, every step forward in lupus research means a lot to a lot of people.)

One of those heroes is Dr Fabien Vincent from the Rheumatology Research Group at Monash University.

Dr Vincent was recently awarded a Rebecca L Cooper Medical Research Foundation Grant for identifying molecular signatures in Indigenous Australians with lupus. 

He said, "We ultimately aim to improve our understanding of treatment of lupus to develop a more targeted and personalised medicine for patients, and help to close the health gap between Indigenous and non-Indigenous Australian lupus sufferers."


He has provided a list of some of the recent publications related to his and the Monash team's lupus research.  Here's the list:


Vincent FB, Kandane-Rathnayake R, Hoi AY, Slavin L, Godsell JD, Kitching AR, Harris J, Nelson CL, Jenkins AJ, Chrysostomou A, Hibbs ML, Kerr PG, Rischmueller M, Mackay F and Morand EF. Urinary B Cell-Activating Factor of the Tumor Necrosis Factor Family (BAFF) in Systemic Lupus Erythematosus. Lupus 2018; 27:2029-40
 
Mende R†, Vincent FB†, Kandane-Rathnayake R, Koelmeyer R, Lin E, Chang J, Hoi A, Morand EF, Harris J† and Lang T†. Analysis of Serum Interleukin (IL)-1b and IL-18 in Systemic LupusErythematosus. Front Immunol 2018; 9:1250
† Equal contributors

Vincent FB, Slavin L, Hoi AY, Kitching AR, Mackay F, Harris J, Kandane-Rathnayake R and Morand EF. Analysis of urinary macrophage migration inhibitory factor in systemic lupus erythematosus. Lupus Sci Med 2018; doi: 10.1136/lupus-2018-000277
 
Vincent FB†, Lin E†, Sahhar J, Ngian GS, Kandane-Rathnayake R, Mende R, Hoi AY, Morand EF, Lang T†, Harris J†. Analysis of serum macrophage migration inhibitory factor and D-dopachrome tautomerase in systemic sclerosis. Clin Transl Immunology 2018; 7:e1042
† Equal contributors
 
Vincent FB†, Nim H†, Thomas JPW, Morand EF† and Harris J†. Effect of storage duration on cytokine stability in human serum and plasma. Cytokine 2019; 113:453-7
† Equal contributors

Vincent FB, Bubicich M, Downie-Doyle S, Mackay F, Morand EF and Rischmueller M. Serum soluble Fas and Fas ligand(FasL) in Primary Sjögren’s Syndrome. Clin Exp Rheumatol 2019 

 Vincent FB, Kandane-Rathnayake R, Hoi AY, Slavin L, Godsell JD, Kitching AR, Harris J, Nelson CL, Jenkins AJ, Chrysostomou A, Hibbs ML, Kerr PG, Rischmueller M, Mackay F and Morand EF. Urinary B Cell-Activating Factor of the TumorNecrosis Factor Family (BAFF) in Systemic LupusErythematosusLupus 2018; 27:2029-40
 
Mende R†, Vincent FB†, Kandane-Rathnayake R, Koelmeyer R, Lin E, Chang J, Hoi A, Morand EF, Harris J† and Lang T†. Analysis of Serum Interleukin (IL)-1b and IL-18 in Systemic LupusErythematosus. Front Immunol 2018; 9:1250
† Equal contributors

Vincent FB, Slavin L, Hoi AY, Kitching AR, Mackay F, Harris J, Kandane-Rathnayake R and Morand EF. Analysis of urinary macrophage migration inhibitory factor in systemic lupuserythematosus. Lupus Sci Med 2018; doi: 10.1136/lupus-2018-000277
 
Vincent FB†, Lin E†, Sahhar J, Ngian GS, Kandane-Rathnayake R, Mende R, Hoi AY, Morand EF, Lang T†, Harris J†. Analysis of serum macrophage migration inhibitory factor and D-dopachrome tautomerase in systemic sclerosis. Clin Transl Immunology 2018; 7:e1042
† Equal contributors
 
Vincent FB†, Nim H†, Thomas JPW, Morand EF† and Harris J†. Effect of storage duration on cytokine stability in human serum and plasma. Cytokine 2019; 113:453-7
† Equal contributors

Vincent FB, Bubicich M, Downie-Doyle S, Mackay F, Morand EF and Rischmueller M. Serum soluble Fas and Fas ligand(FasL) in Primary Sjögren’s Syndrome. Clin Exp Rheumatol 2019 

Vincent FB, Kandane-Rathnayake R, Koelmeyer R, Hoi AY, Harris J, Mackay F and Morand EF. Analysisof serum B cell-activating factor from the tumor necrosis factor family (BAFF)and its soluble receptors in systemic lupus erythematosus. Clin Transl Immunology 2019; 8:e01047



I have to admit some of those articles are over my head (right, I admit it, all of them are over my head, my degrees are in a very different field) - but that's OK  - I don't have to understand the details, I just appreciate that someone who does understand is doing the work.

If you want to read something of Dr Vincent's that is easier for non-scientists to read, here are some of his articles (originally from The Conversation) that have been republished here at sometimesitislupus.com : 






The tenth of May is World Lupus Day - if you want to mark the day by doing something positive to help people with lupus, you might want to donate to lupus research at Monash or other Australian Universities. You can find donation links in the right-hand column of this blog.